Wednesday, September 23, 2015

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Rationale and elements of a successful food-fortification programmer  


To reduce iron-deficiency anemia [10]. However, it has been useful in many countries and has been found to be cost-effective [6, 10]. Chile has used animal blood as a convenient and cheap source of iron for fortification programmed [10]. Venezuela has fortified per-cooked corn flour, to which other micro-nutrients, including vitamin A, have been added. Wheat flour (without vitamin A) has also been fortified with iron successfully on a national basis [15]. The OMNI Project is currently working with the Sri Lankan government to test the efficacy of the fortification of wheat flour with iron for tea plantation workers, with the intention of scaling up to a larger program me when its efficacy has been established. The private sector in Indonesia and other Asian countries is developing instant noodles fortified with iron and other nutrients, aiming initially at a middle-income more than a low-income market.
Salt and other products
Fortification of salt with iron has been implemented on a limited scale in India and Thailand, but although it appears to be technically feasible, it has not, at this time, been adopted more widely [10]. Iron-fortified salt may have a greater role in double fortification (see below). Other vehicles of fortification include rice flour (Argentina and Chile), fish sauce (Thailand), curry powder (South Africa), and such products as barley sprout flour, coffee, grain amaranth cereal, maize meal, potato starch, and wheat flour noodles, all of which are currently being investigated and developed; however, their future on a large and sustainable scale remains uncertain [10]. In Brazil there is an experimental project in some day-care centers to fortify water-filtration systems with iron.
Summary of iron-fortification programmer
Success with iron fortification has involved finding appropriate iron fortification and food vehicles in terms of organoleptic properties, getting government commitment (often by legislation as a political act), and increasing awareness of the extent of the problem of iron deficiency as well as the fact that other interventions have not been particularly sustainable or successful. Fortification with iron has also been shown to be effective, e.g., in Chile and Venezuela [15,19].
Iodine
Iodine has been most vigorously pursued as a fortification of salt for a variety of reasons, especially those factors which lead to or contribute to successful programmer: consumption in fairly consistent amounts by all sectors of society, consumption at roughly consistent levels throughout the year, and technological feasibility and cost-effectiveness. It has also had the advantage of strong international and government commitment and an international experience that has been freely shared. Countries with effective iodized salt programmer have shown sustained reductions in the prevalence of iodine-deficiency disorders [6,10,20]. However, sustainability has not always been ensured, and the populations of countries like China, Germany, and Switzerland showed increases in the prevalence of iodine deficiency where commitment to the programmed was not maintained.
Another problem has been the assumption that fortification could be imposed from the top without the involvement or commitment of consumers and, sometimes, policy makers. This has led, in some cases, to consumer groups suing governments for the right to consume non-iodized salt, e.g., in India, and to both consumers and government not being aware of the importance and significance of iodization in terms of national health and economic productivity. It is essential that people know why their salt is iodized and what the associated benefits are, so that the programmed ensures sustainability through consumer demand. It has also been shown that all salt (including salt intended for animals and industry) must be iodized to ensure the success and sustainability of these programmes [10,20].
Other vehicles of iodization have included bread, sweets, milk, flour, sugar, and condiments. Fortification of animal feeds can be useful in increasing the iodine content of animal products [4]. Dietary intake of iodine can be increased by adding iodine to drinking water (as in schools in Thailand) or to the local water supply (as in China), or by using a commercial attachment to water pumps with slow-release resins, which is currently under trial.
In summary, the success with digitization has been due to its relative technological straightforwardness, much international experience, proven efficacy, and enormous support and advocacy from the international donor community, such as UNICEF and the International Council for the Control of Iodine-Deficiency Disorders (ACIDIC)[20].
Multiple fortification
Multiple fortification of foods is a possible way of addressing deficiencies of two or more micro-nutrients at the same time in a cost-effective manner, although some organizational, technical, and micro nutrient-interaction constraints need to be addressed in developing countries. Nevertheless, progress is being made, e.g., in double fortification of salt with iodine and iron [21]. Multiple fortification has been successful in the more developed countries, particularly in fortification of cereals and infant-weaning foods [10]. In some cases, fortification with two micro nutrients (e.g., iron and vitamin A or iron and vitamin C) would enhance the effects of fortification on micro-nutrient status [6,22].
Nevertheless, it is important to remember that although scientific and engineering advances have resulted in an increasing number of options regarding the choice of mortification compound and processing procedures, there is a limit to the possibilities of new technologies. For example, multiple fortifications of certain food vehicles may result in substantially increased cost and reduced bio availability [23]. Changes in the sensory or narcoleptic characteristics of the food can also be a problem. For example, encapsulation of micro nutrients may not be cost-effective in some countries, even though the technology is theoretically available.
Other micro-nutrients
The focus of the international community has been on the three most prevalent micro nutrient deficiencies (vitamin A, iron, and iodine). Clearly, other micro-nutrients, such as vitamins D, E, and C and the B-complex vitamins, are also likely to be important in many settings and are used as fortification in many coun- tries in different combinations. There is mounting evidence that zinc deficiency may be important in many population groups. However, for focus, and reflecting current international priorities, this paper has only addressed vitamin A, iron, and iodine.

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Abstract
Introduction
Extent of the microelectronic problem
Fortification as a prevention and control approach
Fortification programmer
Constraints to successful programmer
Facilitating factors in successful programmer
Conclusions
Summary
Acknowledgements
References
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Ian Danton-Hill
Ian Danton-Hill is the Project Director for Opportunities for Micro nutrient Interventions (OMANI) at John Snow, Inc., Arlington, Virginia, USA.
Mention of the names of firms and commercial products does not imply endorsement by the United Nations University.
Abstract
Over 2,000 million people, or more than one of three individuals throughout the world, are at risk for iron, vitamin A, or iodine deficiency. The three main approaches to addressing micronutrient deficiencies are fortification, supplementation, and dietary diversification. Although fortification of staple foods has played a significant role in the nutritional well-being and health of the more industrialized nations, it has not been considered an option for less developed countries because of the lack of centrally processed foods and poorly developed food-marketing systems. As food markets expand, however, fortification options are becoming increasingly available. This paper identifies past and present successes and failures, as well as the facilitating factors and constraints that need to be addressed. Based on recent experience and the lessons learned, successful programmer require at least the following: political will and support and the willingness to legislate or regulate; private-sector involvement; public-sector support; willingness of both sectors to enforce quality assurance programmer; good data on consumption patterns; social acceptability of fortified food, implying no change in narcoleptic properties; and minimal change in cost.
Introduction
The elimination of vitamin A deficiency and iodine-deficiency disorders and the substantial reduction of iron-deficiency anemia have been endorsed as achievable goals by more than 159 countries [1]. This paper will look at one of the main strategies being used to address this problem: fortification and the elements of a successful programmer. Other complementary approaches to prevent and control micro nutrient malnutrition include diet diversification, pharmacological supplementation, and public health measures, such as immunization and control of infectious diseases.
Extent of the micro-nutrient problem
Microelectronic malnutrition is a serious threat to the health and productivity of more than 2,000 million people worldwide, even though it is largely preventable [2]. Because of their high prevalence and close association with childhood illness and mortality, the three micro nutrient deficiencies of greatest public health significance are those of iron, vitamin A, and iodine. Women and children are more vulnerable to micro nutrient deficiencies because of their added requirements for reproduction and growth, respectively [3].
Fortification as a prevention and control approach
Fortification is defined by the Codex Implementations as “the addition of one or more essential nutrients to a food, whether or not it is normally contained in the food, for the purpose of preventing or correcting a demonstrated deficiency of one or more nutrients in the population or specific population groups” [4].
Micro nutrient interventions, and particularly fortification, have been identified by the World Bank as among the most cost-effective of all health interventions [5]. There is a wealth of experience in fortifying foods, and it has been a major factor in the control of micro nutrient deficiencies in the industrialized world [6]. It is now being extended in some of the wealthier nations to provide preventive action against deficiencies of nutrients that are not in real shortage in the diets of the general population. For example, in Australia thiamine is added to wheat flour to address the relatively high levels of cerebral degeneration (which are seen, however, in less than 1% of the population) associated with diets low in thiamine and high in alcohol (Knicker-Forsake syndrome) [7]. In the United States flour is fortified with foliage to prevent congenital malformations of the spinal cord (neural tube defects, including spins biddable), which affect approximately 2 in every 1,000 pregnancies [8].
Until recently it was presumed that fortification was not a suitable intervention in the less industrialized countries, since previous experience in developing countries has not always been encouraging [9].